(Hum Virol Retrovirol 2015, 2(7); 00071) Summary: The study evaluated workflow organization and automation improvements to the ViroSeq HIV-1 Genotyping System through the use of semi-automated extraction platforms, automated amplicon quantification, and high-throughput sequencing platforms.
(Presented at 2015 AMP in Austin, TX) Summary: This study evaluated the functionality and performance of a novel prototype plasma separation card that collects capillary blood, separates cellular components by gravity and stores plasma at ambient temperature pending analysis.
Presented at 2015 ASN in San Diego, CA) Summary: This study described the detection of CXCL9/MIG and CXCL-10/IP-10 in urine spectrophotometrically, in combination with a novel collection device ViveST, eliminating the need for cold chain storage.
(Presented at 2015 CVS in Daytona Beach, FL) Summary: In this study sets of molecular diagnostic controls were analyzed in their native frozen state and compared to controls stored on ViveST in a dried, thermostable format.
(Presented at 2015 HEP DART in Maui, HI) Summary: This study evaluated the performance of a novel prototype plasma separation card composed of a polysulfone separation membrane and absorbent collection pad allowing the separation of cellular components and collection/stabilization of plasma at ambient conditions.
Validation of Real-Time PCR Assay for HLA-B*5701 Detection: A Novel and Rapid Pharmacogenomic Test Predicting Abacavir Hypersensitivity Reaction
(Presented at 2014 CVS in Daytona Beach, FL) Summary: A description of the analytical performance of a real-time PCR assay for the detection of the HLA-B*5701 allele.
(Presented at 2014 AMP in Washington, D.C.) Summary: This study evaluated the stability of HIV-1 plasma samples shipped and stored on ViveST, a trasnformational dried ambient temperature storage and transportation device.
(Presented at 2014 AMP in Washington, D.C.) Summary: This study evaluated the stability of HIV-1 plasma samples shipped and stored on ViveST, a transformational dried ambient temperature storage and transportation device.
ING116070: A Study in Pharmacokinetics and Antiviral Activity of Dolutegravir in Cerebrospinal Fluid in HIV-1-infected, ART-Naive Subjects
(Clinical Infectious Diseases Advance Access publication published June 18, 2014) Summary: Median dolutegravir concentrations in cerebrospinal fluid were similar to unbound dolutegravir concentrations in plasma and in all subjects exceeded the in vitro 50% inhibitory concentration for wild-type viruses (0.2 ng/mL) by ≥ 66-fold, suggesting that dolutegravir achieves therapeutic concentrations in cerespinal fluid. HIV-1 SuperLow Viral […]
Detection of Low Level HCV RNA in Room Temperature Stored Samples using ViveST™, a Transformational Storage and Transport Device
(Presented at 2014 CVS in Daytona Beach, FL) Summary: This study evaluated the storage of low titer HCV plasma using ViveST, a transformational dried storage and transport device, in combination with the Abbott RealTime HCV assay.