Research & Studies

At bioMONTR Labs, we believe in nurturing and re-investing in the scientific community.  As a key opinion leader laboratory, we take the opportunity to publish and present the exciting results from many of our assay development efforts.  Summaries are provided below for a few of our recent publications/presentations. Contact us if you are interested in learning more.

Increasing the performance of a fully automated quantitative assay for the detection of circulating HBV pregenomic RNA

(presented at 2021 HEP DART in Los Cabos, Mexico) Summary: A presentation of the increased analytical performance of a fully automated assay for the detection and quantitation of hepatitis B pregenomic RNA in CHB patients.

Hepatitis B pregenomic RNA: Performance of an Automated Real-Time Quantitative Assay

(presented at 2019 CVS in Savannah, GA) Summary:  A presentation of the analytical performance of a new assay for the detection and quantitation of hepatitis B pregenomic RNA in CHB patients.

Prevelence and Correlates of Persistent HIV-1 RNA in Cerebrospinal Fluid During Antiretroviral Therapy

(The Journal of Infectious Diseases 2017;215:105-13) Summary:  bioMONTR Labs’ proprietary HIV-1 SuperLow Assay was utilized to measure HIV-1 RNA levels in CSF and plasma from adults taking suppressive ART to assess if the association between HIV-1 RNA discordance and HAND may reflect compartmentalization.

Validation of eMAG™ for HIV-1 Low Viremia Testing

(Presented at 2017 CVS in Savannah, GA) Summary: A presentation of the validation for using the eMAG with bioMONTR Labs’ HIV-1 SuperLow assay, a RESEARCH USE ONLY for detection of single copy HIV-1 RNA.

Full Automation and Flexibility for Extraction of Free Circulating Nucleic Acids: Proof of Concept for eMAG™

(Presented at 2017 CVS in Savannah, GA) Summary: This study evaluated the use of eMAG for fully automated extraction of free circulating nucleic acids.

Workflow Optimization of the ViroSeq™ Human Immunodeficiency Virus-1 (HIV-1) Genotyping System

(Hum Virol Retrovirol 2015, 2(7); 00071) Summary: The study evaluated workflow organization and automation improvements to the ViroSeq HIV-1 Genotyping System through the use of semi-automated extraction platforms, automated amplicon quantification, and high-throughput sequencing platforms.