Increasing the performance of a fully automated quantitative assay for the detection of circulating HBV pregenomic RNA
(presented at 2021 HEP DART in Los Cabos, Mexico) Summary: A presentation of the increased analytical performance of a fully automated assay for the detection and quantitation of hepatitis B pregenomic RNA in CHB patients.
Hepatitis B pregenomic RNA: Performance of an Automated Real-Time Quantitative Assay
(presented at 2019 CVS in Savannah, GA) Summary: A presentation of the analytical performance of a new assay for the detection and quantitation of hepatitis B pregenomic RNA in CHB patients.
Prevelence and Correlates of Persistent HIV-1 RNA in Cerebrospinal Fluid During Antiretroviral Therapy
(The Journal of Infectious Diseases 2017;215:105-13) Summary: bioMONTR Labs’ proprietary HIV-1 SuperLow Assay was utilized to measure HIV-1 RNA levels in CSF and plasma from adults taking suppressive ART to assess if the association between HIV-1 RNA discordance and HAND may reflect compartmentalization.
Validation of eMAG™ for HIV-1 Low Viremia Testing
(Presented at 2017 CVS in Savannah, GA) Summary: A presentation of the validation for using the eMAG with bioMONTR Labs’ HIV-1 SuperLow assay, a RESEARCH USE ONLY for detection of single copy HIV-1 RNA.
Full Automation and Flexibility for Extraction of Free Circulating Nucleic Acids: Proof of Concept for eMAG™
(Presented at 2017 CVS in Savannah, GA) Summary: This study evaluated the use of eMAG for fully automated extraction of free circulating nucleic acids.
Workflow Optimization of the ViroSeq™ Human Immunodeficiency Virus-1 (HIV-1) Genotyping System
(Hum Virol Retrovirol 2015, 2(7); 00071) Summary: The study evaluated workflow organization and automation improvements to the ViroSeq HIV-1 Genotyping System through the use of semi-automated extraction platforms, automated amplicon quantification, and high-throughput sequencing platforms.
Novel Plasma Separation Cards for Collection in Resource-Limited Settings
(Presented at 2015 AMP in Austin, TX) Summary: This study evaluated the functionality and performance of a novel prototype plasma separation card that collects capillary blood, separates cellular components by gravity and stores plasma at ambient temperature pending analysis.
Detection of Inflammatory Biomarkers in Urine using a Dried, Shelf Stable Transport Device, ViveST®
Presented at 2015 ASN in San Diego, CA) Summary: This study described the detection of CXCL9/MIG and CXCL-10/IP-10 in urine spectrophotometrically, in combination with a novel collection device ViveST, eliminating the need for cold chain storage.
Room Temperature Stable, Dry-Transport Technology for Molecular Diagnostic Controls
(Presented at 2015 CVS in Daytona Beach, FL) Summary: In this study sets of molecular diagnostic controls were analyzed in their native frozen state and compared to controls stored on ViveST in a dried, thermostable format.
Proof of Concept: Novel Plasma Separation Cards for HCV/HIV Quantification
(Presented at 2015 HEP DART in Maui, HI) Summary: This study evaluated the performance of a novel prototype plasma separation card composed of a polysulfone separation membrane and absorbent collection pad allowing the separation of cellular components and collection/stabilization of plasma at ambient conditions.